Topic outline

  • General

    Meta-analysis of diagnostic accuracy studies

  • Session 1

    Session 1 covers the topics described on the following table. Press the pdf icon to download the related material. The same counts for the next sessions (2-5).

    Session

    Topic

    Duration

    Online

    Face-face

    Sessiοn 1

    Session 1 material  

    Overview tο Systematic Reviews

     

    1 week

     

    8 hours

    Introduction to diagnostic tests and diagnostic accuracy studies (DAS)

    Concepts and Importance of diagnostic test studies

    Stages in the development of a diagnostic accuracy test

    • Session 2

      Session

      Topic

      Duration

      Online

      Face-face

      Session 2

      Session 2 material

      The meta-analysis study protocol (one test for demo)

      1 week

      8 hours

      Defining the problem and test of interest

      Introduction part of the protocol

      Defining the objectives / research questions

      Defining the article selection criteria

      Defining the article search strategies

      • Session 3

        Session

        Topic

        Duration

        Online

        Face-face

        Session 3

        Session 3 material

        Searching for articles

        1 week

        8 hours

        Using medical databases e.g. Pubmed

        The first stage of article selection

        The QUADAS tool for assessing the quality of articles & final selection

        Home work – Search for articles

        • Session 4

          Session

          Topic

          Duration

          Online

          Face-face

          Session 4

          Session 4 material

          Data management

          1 week

          8 hours

          Selection and prioritization of study variables

          Data extraction and summarization

          Data extraction and summarization - Secondary study variables

          Data analysis for pooled sensitivity, specificity, Forest plots, etc

          Analysis for Heterogeneity in primary study reports

          Results interpretation

          • Session 5

            Session

            Topic

            Duration

            Online

            Face-face

            Session 5

            Session 5 material

            Meta-analysis manuscript

            1 week

            8 hours

            Review of the STARD and other tools for reporting DAS

            Meta-analysis study manuscript preparation

            Biases and Challenges in meta-analyses of diagnostic tests

            Challenges in conducting and publishing a meta-analysis study